Naturext Immune+ AC Essence™ 牛樟芝

 

AC Essence

Price Information

Weight
Price
1 box / 60 capsules
$155.00
1 box / 60 capsules
$144.20

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NaturextTM Immune+ AC Essence is made from Antrodia Camphorata Mycelia, a Rare Fungus found naturally only in Taiwan and have been used by the Chinese as a Cancer Preventive Health Supplement for more than 50 years.

Antrodia Camphorata is rich in Flavonoids, Terpenoids, Polyphenolics and Polysaccharides. The known main Bioactive Compounds found in AC are: Polysaccharides, Superoxide Dismutase (SOD), and Triterpenes.

Triterpenes, the most important Bioactive Ingredient found in AC, is a compound which exhibits Anti-Cancer, Anti-Virus, Anti-Oxidant, Hepatoprotection and Cholesterol Inhibition Properties.     



Antrodia Camphorata (AC) is also commonly called the King of Lingzhi. AC is a rare medicinal fungus that grows naturally inside the Cinnamonum Kanehirae Tree Trunk, a native tree species of Taiwan.

Antrodia Camphorata, is a precious Traditional Chinese Herbal Medicine and shows several Pharmacological Effects including the inhibition of proliferation and growth in cancer cells, the inhibition of inflammatory response, the antioxidant and free radical-scavenging activities and the prevention of hepatotoxicity.
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牛樟芝也被称为“灵芝之王”
牛 樟芝属于菌类,是珍贵的药用真菌,寄生于台湾独有的牛樟树树干内。牛樟芝是一种珍贵的传统中药,并有研究显示对肿瘤细胞有抑制其增殖和生长,抑制炎症反 应,抗氧化,清除自由基活性和保肝等若干个药理作用。 牛樟芝,因具有药用价值而闻名,用于中药治疗在台湾已有50多年之久。牛樟芝含有丰富的异黄铜,三萜类化合物,多酸类和多糖体。在牛樟芝里发现的生物活性 化合物:多糖体,超氧化物歧化酶(SOD)和三萜类。其中,三萜类是在牛樟芝里发现的最重要的生物活性成分化合物,它具有抗癌,抗病毒,抗氧化,保肝和抑 制胆固醇的作用。

 


Potentially more potent than Ganoderma Lucidium

Antrodia Camphorata (AC) has been proven to be more potent than Ganoderma Lucidium (Lingzhi) in pharmacological activities. Compared to the well known Ganoderma Licudium (Lingzhi) where less than 50 types of Triterpenes are found, AC contains more than 200 types of Triterpenes. In addition, the concentration of Triterpenes found in AC is 10-15 times higher than Ganoderma Lucidium.

牛樟芝的药理活性远高于灵芝
牛樟芝的三萜类含量远超于灵芝两者相比较,灵芝发现的三萜类不超过50种,而牛樟芝发现的三萜类超过了200种。此外,在牛樟芝的三萜类含量是灵芝的10-15倍。

 

 

 


AC Essence Product Information

Naturext Immune+ AC EssenceTM also uses a patented solid state fermentation process to cultivate Antrodia Camphorata to ensure highest quality and consistency in its manufacturing process. In vitro experiments have shown that the cultivated Naturext Immune+ AC EssenceTM with active anti cancer compound Antroquinonol demonstrated suprior anti cancer cell viability performance against wild Antrodia Camphorata.

Ingredient:
Powder of cultured Antrodia Camphorata Mycelia.

APPLICATIONS:

Anti-allergenic, strengthen immune function
Anti-cancer, chemoprevention
Anti-fatigue, anti-oxidation, anti-LDL cholesterol synthesis
Anti-viral Hepatitis, Anti-hepatoxication, Hepatoprotection
Autoimmune diseases

Chronic Hepatitis B - Detail Complimentary & Adjuvant Application Chart:          


 
Disclaimer: This information is intended for physician information purposes only and is not intended as a substitute for advise from a physician or other health care professional and should not be used for the diagnosis or treatment of any health problem or for prescription of any medication or other treatment. Do not discontinue any other medical treatments without first consulting your doctor.

New Anti Cancer compound isolated from AC
Recently, scientists isolated an anti cancer compound in AC and patented and named the new bio-active compound Antroquinonol1. Various laboratory tests using AntroquinonolTM show that it was effective against a wide range of cancerous cells1. In 2010 March, AntroquinonolTM was recognized as Breakthrough Drug by the Chinese Ministry of Science and Technology. AntroquinonolTM comes with 6 FDA patents and has been approved as IND by the US FDA, currently into second stage clinical trial.
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从牛樟芝里分离出新的抗癌化合物
近年来,科学家从牛樟芝上面分离出一种抗癌化合物和获得专利并命名为新的生活性化合物 Antroquinonol1 。
Antroquinonol  的各种体外试验显示,它对多项癌症具有一定的效果。2010年3月,中国科技技术部承认
Antroquinonol 为突破性新药。 Antroquinonol  配备了6项美国FDA专利,美国FDA批准进入临床试验第一阶段。

References: 1: Planta Med. 2007 Oct;73(13):1412-5. Epub 2007 Oct 11.
"A new cytotoxic agent from solid-state fermented mycelium of Antrodia Camphorata."


Antroquinonol 

New Chemical Entity isolated from Antrodia Camphorata:

 

High safety, high performance anti cancer compound.


Pharmacological Properties and Mechanism of Actions:

Antroquinonol is a MEK1 inhibitor, targeting the Ras/Raf/MEK/ERK pathway, it also decrease the PI3K/Akt/mTOR expression.

AntroquinonolTM could inhibit proferation of liver, lung, breast and prostate cancer cells. AntroquinonolTM
induced S phase arrest of HepG2 cells when they are pretreated with synchronization. After synchronization with Antroquinonol, it decreases all cell cycle regulatory protein and cell growth related protein (including cyclin A, cyclin D, cyclin E, cdk2, cdk4, Rb, p53, Akt and MAPK). Antroquinonol inhibits protein synthesis through translation related protein 4E-BP1 and elF4E.

AntroquinonolTM for the treatment of multiple forms of cancer has been proven in vivo. The compound has passed in-vivo efficacy, ADME/toxicology for at least three kinds of cancer (NSCLC, liver and breast cancer) compared with the chemotherapy drugs Mitomycin and Taxol as positive control. No drug resistance was observed during in-vivo studies. This indicates that the drug can be considered a long-term orally-administered cancer therapy.

 

Antroquinonol MTT ASSAY            人体癌细胞体外试验: 

Antroquinonol    MTT ASSAY*:  

IC 50  (ug/ml)  

Colon cancer  
WiDr  

0.92  

Osteosarcoma (Bone) 

MG-63  

2.09  

Pancreatic 

BxPC-3  

1.44  

Oral Squamous Cell Carcinoma   

SCC-25  

1.05  

Bladder Cancer  

TSGH 8301  

1.05  

Gastric Cancer 

TSGH 9201  

1.32  

Lymphoma 

U937  

9.71  

Squamous Carcinoma (Skin)  

A431  

0.18  

Serous Cystaden Carcinoma (Ovarian) 

ES-2  

0.80  

Hormone Sensitive Hepatoma   

Hep 3B  

0.05  

Non-hormone Sensitive Hepatoma

HepG2  

1.68  

Non Small Cell Lung Cancer 

A459  

0.45  

Hormone sensitive Prostate Cancer 

LNCaP  

2.38  

Primitive neuroectodermal tumor  

SK-N-MC P10  

0.05  

Non-hormone sensitive Prostate Cancer  

DU145  

1.81  

Hormone Sensitive Breast Cancer  

MCF-7  

0.85  

Non-hormone Sensitive Breast Cancer  

 MDA-MB-231  

1.03  



Toxicology studies completed to date have shown toxic effects present only after administration of 30-50 times effective dosage. 

Such symptoms include diarrhea and non-systemic toxic reactions. Compared to other anti-cancer drugs on the market, Antroquinonol® is the only such natural compound that does not elicit side effects.
PD/PK studies have shown that Antroquinonol® bioactivity begins immediately upon being absorbed through the mucosa, allowing for convenient oral administration. Furthermore, studies have shown that the drug does not remain in the body after a period of 13-15 hours.


 

 

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